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Bioreactor Design and Operation - PDF Free Download

Bioreactors are mainly constructed with 316 SS wetted parts. With animal cell cultures, 316L SS is common. Non-product contact surfaces are generally constructed of 304 SS. Geometric dimensions greatly impact bioreactor performance. Microbial cultures generally have a height to diameter ratio (H/DR) of 2e3:1.

Mixing in Bubble Column and Airlift Reactors - ScienceDirect

Oct 01, 2004 · Compared with the two airlift reactors (a split-cylinder and a draft-tube sparged device, both of aspect ratio 9.1), the bubble column (aspect ratio = 9.1) had a shorter mixing time at any aeration rate (superficial aeration velocity of up to 0.05 m s −1 in all reactors). Values of the various mixing parameters in the two fluids were quite .

Mammalian Cell Bioreactor System - [PPT Powerpoint]

Jan 16, 2016 · Most important bioreactor for animal cell culture. Airlift FermenterTall column with an inner draught tube (for fluid circulation)Long column for minimize bubble or foam damage. Ceramic BioreactorConsist of multiple channels which run through the length of a ceramic cylinder.Channel is a square and inner surface area for cell attachment.

Airlift Bioreactors: Review of Recent Advances

Sauter-mean bubble diameter. The last measurements were related to the gas pressure in the tubular membranes that acted as spargers, and *Author to whom correspondence may be addressed. E-mail address: [email protected] bgumail.bgu.ac.il Airlift Bioreactors: Review of Recent Advances By José C. Merchuk*

PPT – Bubble Column Reactors PowerPoint presentation .

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Bubble-Column and Airlift Photobioreactors for Algal Culture

the working aspect ratio was about 10. Data were obtained in tap water for a base-line . gas]liquid hydrodynamics and mass transfer in bubble columns and airlift bioreactors, as comprehensively discussed in major treatise Chisti and Moo-Young, 1987; Chisti, 1989, . height was about 2 m in all cases. Other geometric details,

1,215 Bioreactor PPTs View free & download | PowerShow.com

Bioreactor PowerPoint PPT Presentations. All Time. Show: Recommended. Sort by: Bioreactors Market - Global . Bioreactors Market - Global bioreactors market is set to witness a healthy CAGR of 10.35% in the forecast period of 2019- 2026. Global bioreactors market is set to witness a healthy CAGR of 10.35% in the forecast period of 2019- 2026. .

Airlift Bioreactors: Review of Recent Advances

Sauter-mean bubble diameter. The last measurements were related to the gas pressure in the tubular membranes that acted as spargers, and *Author to whom correspondence may be addressed. E-mail address: [email protected] bgumail.bgu.ac.il Airlift Bioreactors: Review of Recent Advances By José C. Merchuk*

Bioreactor PPT - LinkedIn SlideShare

• The vessel used for bubble column bioreactors is usually cylindrical with an aspect ratio of 4-6 (i.e., height to diameter ratio). 11. AIRLIFT BIOREACTORS • In the airlift bioreactors, the medium of the vessel is divided into two interconnected zones by means of a baffle or draft tube.

Fermenter/Bioreactor - Orbit Biotech

A Fermenter/bioreactor is a vessel used to provide optimum conditions for the controlled growth of microorganisms/ cells by regulating agitation, temperature, and aeration.The main components of fermenter are agitators, spargers, baffles, cooling jacket, pH probes, temperature probes, acid probes, dissolved oxygen probes (DO probes) etc. Bioreactors can be operated in a batch, fed-batch or .

MIXING IN BUBBLE COLUMN AND AIRLIFT REACTORS

Mixing in the axial direction in a bubble column is characterized by an axial dispersion coefficient, E z, which is mainly a function of aeration rate, the geometry of the column and the properties of the fluid (Deckwer et al., 1974; Shah et al., 1982). In airlift bioreactors, the riser and downcomer zones can have different values of E

Bubble-Column and Airlift Photobioreactors for Algal Culture

the working aspect ratio was about 10. Data were obtained in tap water for a base-line . gas]liquid hydrodynamics and mass transfer in bubble columns and airlift bioreactors, as comprehensively discussed in major treatise Chisti and Moo-Young, 1987; Chisti, 1989, . height was about 2 m in all cases. Other geometric details,

Fermenter/Bioreactor - Orbit Biotech

A Fermenter/bioreactor is a vessel used to provide optimum conditions for the controlled growth of microorganisms/ cells by regulating agitation, temperature, and aeration.The main components of fermenter are agitators, spargers, baffles, cooling jacket, pH probes, temperature probes, acid probes, dissolved oxygen probes (DO probes) etc. Bioreactors can be operated in a batch, .

Hydrodynamics and mass transfer in bubble column .

Feb 15, 2017 · The performance of four bioreactors (bubble column, concentric tube airlift, concentric tube stirred airlift, and mechanically stirred tank) were evaluated in this study in terms of the hydrodynamics and mass transfer, using viscous a Newtonian fluid (glycerol 65%) and a non-Newtonian fluid (xanthan 0.25%).

MIXING IN BUBBLE COLUMN AND AIRLIFT REACTORS

Mixing in the axial direction in a bubble column is characterized by an axial dispersion coefficient, E z, which is mainly a function of aeration rate, the geometry of the column and the properties of the fluid (Deckwer et al., 1974; Shah et al., 1982). In airlift bioreactors, the riser and downcomer zones can have different values of E

Air Lift Fermenters and Airlift BioReactors for .

Airlift systems are similar to bubble column reactors where oxygen transfer, internal circulation, and mixing are achieved by bubbling air. They differ however in that air lift bioreactors contain an inner draft tube that creates the drafting force required for liquid circulation and possible improvement of bulk mixing.

Bioreactors for Suspension Culture, Cell Damage in Stirred .

• For air-lift and bubble column bioreactors the aspect ratio (ratio between height and diameter) should be ~14 for small scale and 6–7 for large scale. • A suitable additive such as Pluronic®–F68 should be used whenever feasible.

The interfacial area in external-loop airlift bioreactors

The proposed model of D ax for an external-loop airlift bioreactor is based on the stochastic analysis of the two-phase flow in a cocurrent bubble column and modified for .

Difference Between Bioreactor and Fermentor

Jul 24, 2018 · The six bioreactor designs are continuous stirred tank bioreactors, bubble column bioreactors, airlift bioreactors, fluidized bed bioreactors, packed bed bioreactors, and photo-bioreactors. What is a Fermentor. Fermentor is a type of bioreactor, which uses fungi or bacteria for the fermentation of ethanol or lactic acid.

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Bioreactor PowerPoint PPT Presentations. All Time. Show: Recommended. Sort by: Bioreactors Market - Global . Bioreactors Market - Global bioreactors market is set to witness a healthy CAGR of 10.35% in the forecast period of 2019- 2026. Global bioreactors market is set to witness a healthy CAGR of 10.35% in the forecast period of 2019- 2026. .

airlift bioreactor ppt downcomer gas nozzle riser shear .

Abstract−The effect of mode of sparging gas on the mixing parameters of an internal loop airlift bioreactor was in vestigated Two bioreactors of identical volume of 14 215 103 cm3 and the optimum riser to downcomer cross sectional area ratio of 0 6 were studied In one bioreactor a gas sparger was located in the draft tube and in the annulus in

PPT – Bubble Column Reactors PowerPoint presentation .

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4 Bioreactor Considerations - [PPTX Powerpoint]

Nov 12, 2015 · Some mechanically agitated reactors operating over 20 rpm and bubble column/airlift bioreactors operating at high aeration rates may cause shear damage to cells. Shear sensitivity is strain dependent.Well-controlled homogeneous environmental conditions (T, pH, DO) and supply of CO2-enriched air must be provided.A large support material surface .

Bioreactor Design - Future is BioTechnology.

In designing such a bioreactor, the height of liquid to tank diameter (H:D) is about 2:1, a common ratio of H:Dis also about 3:1; in bakers' yeast production the ratio of H:Dis 6:1. In bubble columns the hydrodynamics and mass transfer depend on the size of the bubbles and how they are released from the sparger.

Slide 1

Bubble column reactors. These are tall reactors which use air alone to mix the. . A differentiation between the three phase fluidized bed and the airlift bioreactor would be made on the basis that the latter have a physical internal arrangement (draft tube) which provides aerating and non-aerating zone . Column bioreactors.

airlift bioreactor ppt downcomer gas nozzle riser shear .

Abstract−The effect of mode of sparging gas on the mixing parameters of an internal loop airlift bioreactor was in vestigated Two bioreactors of identical volume of 14 215 103 cm3 and the optimum riser to downcomer cross sectional area ratio of 0 6 were studied In one bioreactor a gas sparger was located in the draft tube and in the annulus in

Airlift Bioreactors: Hydrodynamics and Rheology .

The bubble column and airlift bioreactors are pneumatically agitated and often employed in bioprocesses where gas-liquid contact is important. The role of the gas is to provide contact with the liquid for mass transfer processes such as absorption or desorption and to provide energy through gas expansion or bubble buoyancy for liquid mixing.

1,215 Bioreactor PPTs View free & download | PowerShow.com

Bioreactor PowerPoint PPT Presentations. All Time. Show: Recommended. Sort by: Bioreactors Market - Global . Bioreactors Market - Global bioreactors market is set to witness a healthy CAGR of 10.35% in the forecast period of 2019- 2026. Global bioreactors market is set to witness a healthy CAGR of 10.35% in the forecast period of 2019- 2026. .

Fermenter/Bioreactor - Orbit Biotech

A Fermenter/bioreactor is a vessel used to provide optimum conditions for the controlled growth of microorganisms/ cells by regulating agitation, temperature, and aeration.The main components of fermenter are agitators, spargers, baffles, cooling jacket, pH probes, temperature probes, acid probes, dissolved oxygen probes (DO probes) etc. Bioreactors can be operated in a batch, .

Airlift Bioreactors - an overview | ScienceDirect Topics

Airlift bioreactors are tower reactors for large-scale aerobic cultures where the mixing of the culture broth is done by the inserted gas via an airlift pump (Fig. 7.5).This pump injects compressed air at the bottom of the discharge pipe, which is immersed in the liquid. The compressed air mixes with the liquid, causing the gas–liquid mixture to be less dense than the rest of the liquid .